Respiratory Medicine CME
Volume 2, Issue 1 , Pages 25-26, 2009

Mesothelioma – A change in the natural history?

Distant cutaneous and soft tissue metastases following chemotherapy

  • S.V. Fletcher

      Affiliations

    • Respiratory and General Medicine, Southampton University Hospitals Trust, Tremona Road, Southampton SO16 6YD, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 (0) 7904044523.
  • ,
  • D.E. Laws

      Affiliations

    • Respiratory and General Medicine, The Royal Bournemouth Hospital, Castle Lane East, Bournemouth, Dorset BH7 7DW, UK
  • ,
  • J. McCutcheon

      Affiliations

    • The Royal Bournemouth Hospital, Castle Lane East, Bournemouth, Dorset, BH7 7DW, UK
  • ,
  • P. Perkins

      Affiliations

    • The Southbourne Surgery, 17 Beaufort Road, Bournemouth, BH6 5BF, UK

Received 23 August 2008; accepted 15 October 2008.

Summary 

Mesothelioma is a rare tumour arising from the serosal surfaces of the pleura, peritoneum and other body cavity linings. Distant cutaneous metastases of mesothelioma are rarely noted but have been previously reported. This case demonstrates both cutaneous and soft tissue metastases to the kidney, lung, thyroid, lymph nodes and tongue from a pleural malignant mesothelioma. These metastases were demonstrated during the lifetime of the patient, most are noted post-mortem. To the best of our knowledge, this distribution of both cutaneous and soft tissue metastases has not previously been reported. We propose that as the incidence of mesothelioma increases and life expectancy is altered by treatment, metastases may be a more common occurrence.

Keywords: Mesothelioma, metastases, chemotherapy

 

PII: S1755-0017(08)00087-0

doi:10.1016/j.rmedc.2008.10.001

Respiratory Medicine CME
Volume 2, Issue 1 , Pages 25-26, 2009