Respiratory Medicine CME
Volume 1, Issue 2 , Pages 100-102, 2008

Severe idiopathic hypereosinophilic syndrome

Division of Pulmonary and Critical Care Medicine, Department of Medicine, VA Medical Center, Indiana University School of Medicine, 1481 West Tenth Street, 111P-IU, Indianapolis, IN 46202, USA

Received 30 November 2007; accepted 18 December 2007.

Summary 

Hypereosinophilic syndrome (HES) is a systemic illness that usually presents with nonspecific symptoms. However, HES can be fatal, particularly when eosinophils infiltrate vital organs. We report a patient with HES who presented with a perforated viscus and sepsis-like syndrome and rapidly improved with drotrecogin-alfa and steroid therapy.

Keywords: Eosinophil, Bronchoalveolar lavage, Colon, Heart, Drotrecogin alfa, Corticosteroids

 

PII: S1755-0017(08)00005-5

doi:10.1016/j.rmedc.2007.12.005

Respiratory Medicine CME
Volume 1, Issue 2 , Pages 100-102, 2008